Lokomotiv 1929 Mezdra (Bulgarian: Локомотив 1929 Мездра) was a Bulgarian football club from the city of Mezdra.

The team was founded in 2011 before the dissolution of the original club PFC Lokomotiv Mezdra.

In 2012 its promoted to V Group and got to the Third Round of the Bulgarian Cup, but it was drawn from V Group and sent to Regional Group.

In 2015, the team qualified again for the Bulgarian Cup, but lost in the First Round to the Bulgarian champion Ludogorets Razgrad.