5IY6, 5IY9, 5IY8, 5IYA, 5IYB, 5IY7, 5IYC, 5IYD543466420ENSG00000099817ENSMUSG00000004667P19388Q80UW8NM_002695NM_001316323NM_001316324NM_025554NP_001303252NP_001303253NP_002686NP_079830DNA-directed RNA polymerases I, II, and III subunit RPABC1 is a protein that in humans is encoded by the POLR2E gene.

[5] This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes.

This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits.

An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit.

[9] This article on a gene on human chromosome 19 is a stub.