1CQT545018985ENSG00000110777ENSMUSG00000032053Q16633Q64693NM_006235NM_011136NP_006226NP_035266POU domain class 2-associating factor 1 is a protein that in humans is encoded by the POU2AF1 gene.

[5][6] The protein is also termed Oct coactivator from B cells (i.e. OCAB), Oct binding factor 1 (OBF1 or OBF-1), and, as commonly found in the literature, BOB1.

[7] BOB1 is a transcriptional coactivator (i.e. a protein that controls the activity of transcription factors) which is expressed principally by B-cell lymphocytes and controls immunoglobulin and other genes critical for these cells expression of CD20, CRISP-3, and CD36.

[8] The expression of BOB1 has proven useful for identifying certain lymphomas as being B-cell lymphomas,[9] as exemplified in studies which use BOB1 expression to help identify lymphomas as being diffuse large B-cell lymphomas, not otherwise specified.

This article on a gene on human chromosome 11 is a stub.