The PZL.49 Miś (English: Little Bear) was a Polish twin-engined medium bomber design that remained only a project due to the outbreak of World War II.

The PZL.49 was a development of the advanced, "state-of-the-art"[1] medium bomber PZL.37 Łoś, designed by Jerzy Dąbrowski, Stanisław Kot and Piotr Kubicki.

The main target for the design team was to increase performance, especially flight speed, by means of installing more powerful engines and improving aerodynamics.

Design process was slow due to the simultaneous involvement of PZL construction bureau in development of the PZL.50 Jastrząb fighter.

A development schedule from August 1939 set the first flight of PZL.49/I in the summer of 1940, with the first serial built aircraft being delivered to combat units in late 1941 or early 1942.

In terms of size, it was slightly larger than the Lockheed Model 10 Electra that Amelia Earhart used and was comparable to its predecessor, the PZL.37 Łoś.