Pablo E. Macías Valenzuela (November 15, 1891 - April 30, 1975) was a Mexican military man and politician.

He was born on November 15, 1891, in the Rancho de Las Cabras, El Fuerte, Sinaloa.

On March 25, 1912, he began his military career when he joined the Maderista forces in the 4th Sonora Irregular Battalion.

On April 20, 1914, General Álvaro Obregón granted him the rank of Infantry Major.

He was head of several military operations, Secretary of National Defense from December 1, 1940 to September 1, 1942 and constitutional governor of Sinaloa from 1945 to 1950.