He worked as a session musician before collaborating with Juan Michelena in the protest album "Dicen que soy..." in 1977 and joining Vytas Brenner's Venezuelan fusion band Ofrenda.
In 1979 he released Cosas Sencillas, his first solo album and began a successful career as composer and producer of many Latin artists and bands.
He then interrupted his career after receiving a scholarship from the Venezuelan Government to study film scoring in Berklee College of Music.
Afterward, he worked as producer and composer for other Venezuelan acts like Melissa, Kiara and Ilan Chester.
Thereafter, Manavello moved to Miami, Florida, where he continued to produce records for Olga Tañón and Luis Fonsi, among others.