Pagno di Lapo Portigiani (1408 — 1470) was an Italian Renaissance decorative sculptor, a minor follower of Donatello who worked on numerous occasions in projects designed and supervised by Michelozzo.
In 1426-28 Pagno di Lapo was working as a stone-cutter in the joint shop of Donatello and Michelozzo in Pisa, during the production of the Coscia and Brancacci tombs.
In 1428 he collaborated with two obscure stone-cutters on the decorative elements of the baptismal font in the Duomo of Siena, and as a garzone in Donatello's shop in connection with the resumed work on the pulpit for Prato, 1434.
Basing their attributions on Giorgio Vasari, a significant number of Early Renaissance sculptures have been associated with Pagno's name since the late nineteenth century, most notably the Madonna and Child at the Museo dell'Opera del Duomo.
The sole surviving identifiable work by Pagno di Lapo is the inscribed tabernacle frame, which Jansen found "shows him to have been a skillful carver of ornament, but the plastic décor of the structure contains so little of true sculpture that it yields small evidence of his artistic ability.