The Painting of Lady Tjepu is a fragment from a large fresco from Tomb 181 in Thebes (Luxor).

Son and mother stand before a shrine, where they bring an offering for the Beautiful Festival of the Valley in honour of the deity Amun.

In accordance with tradition, Tjepu is not shown at her real age, but in an idealised, youthful form.

The image is dated to the late 18th Dynasty, in the reign of Pharaoh Amenhotep III (1390–1353 BC).

The image entered the Brooklyn Museum in 1916 as part of the collection of Charles Edwin Wilbour, where it remains a key piece of the ancient Egyptian collection to this day (inventory number 65.197).