[1][2] The ODI series formed part of the inaugural 2020–2023 ICC Cricket World Cup Super League.

[6] England won the first two ODI matches to win the series with a game to spare.

[16] On 8 July 2021, Pakistan's Haris Sohail was ruled of the ODI matches due to hamstring injury.

[18] However, on 6 July 2021, it was announced that seven individuals, three squad members and four support staff,[19] had tested positive for COVID-19.

[22] Prior to the ODI series, the Pakistan team were scheduled to play two 50-over intra-squad practice matches.