The PalaLottomatica Rome, together with Mediolanum Forum of Milan, is a member of the European Arenas Association (EAA).

Palazzo dello Sport was designed by architect Marcello Piacentini, in 1957, and its reinforced concrete dome was engineered by Pier Luigi Nervi.

It was made more functional, especially in terms of acoustics, in order to be able to accommodate important musical events.

An audience of over 14,000 spectators was disappointed, due to a 3–2 comeback victory in Italy, after a thrilling game that lasted over two hours.

[6] Many artists have performed at the Palazzo dello Sport / PalaLottomatica since the late 1960s and early 1970s: among them, the Rolling Stones in 1970,[7] Depeche Mode several times since 1987,[8][9] the Cure,[10] Paul McCartney,[11] Iron Maiden,[12] Dire Straits[13] Bon Jovi, and many others.

In 1975, a Lou Reed concert was cancelled because of turmoil between the police and groups of people who were protesting against the high prices of concert tickets; because of that turmoil, the Palazzo dello Sport was seriously damaged,[14] and foreign artists refused to perform in Italy for the next five years,[15] until Bob Marley performed in Milan in 1980.