It was built on the designs to architect Carlo Gimach in the Mannerist style, the first in Valletta and very unusual to the period.
It was sold to the Manoel Foundation in 1732, and it was let to Grand Master Ferdinand von Hompesch zu Bolheim from 1787 to 1798.
[3] The palace was the residence of John Hookham Frere and his wife Elizabeth Jemima, dowager Countess of Erroll[1] from 1821.
At this palace the Frere couple had looked after an orphaned girl, named Statyra Livedestro, who Frere had rescued from the sea of Turkey; this happened when the Christian Greeks were expelled from Turkey by orders of Kemal Atatürk, that before the event was Greek land, during the exchange of Turkish-Greek population in the early 19th-century.
[4] In the late 19th century, the palace became the main residence of Marquis Emmanuele Scicluna, the President of La Borsa.