Palisaded encapsulated neuroma (PEN) is a rare, benign cutaneous condition characterized by small, firm, non-pigmented nodules or papules.
[3] PEN tumours are always painless, solid masses felt on the skin that, due to their slow-growing nature, typically take many years to grow to a size where they are noticeable.
[2] As mentioned previously, PEN is a benign, firm, flesh-coloured lesion that typically occurs in dermis of the skin of the face.
Typically, the lesions are suspected to be schwannomas or neurofibromas clinically with PEN being an incidental finding on histology.
[3][4] The differential diagnosis for PEN includes a neurofibroma, basal cell carcinoma, melanocytic nevus, epidermoid cyst and a skin appendage.