Palmetto College is part of the University of South Carolina System.
Students who have 60 college credit hours can be admitted to Palmetto College and receive a bachelor's degree.
Palmetto College was funded by a $5M appropriation by the South Carolina General Assembly in 2012.
In January 2013, Susan Elkins was named the first chancellor.
Palmetto College officially started enrolling students on April 18, 2013.