Leslie Pamela Cook-Ioannidis (born c. 1945) is an American mathematician, the Unidel Professor of Mathematical Sciences and Professor of Chemical Engineering at the University of Delaware.

[1] She was the president of the Society for Industrial and Applied Mathematics (SIAM) for 2015–2016.

[5] At the University of Delaware, she was chair of the Department of Mathematical Sciences for nine years before becoming associate dean of engineering.

[1] With Julian Cole, she is the author of the book Transonic Aerodynamics (North-Holland, 1986).

[6][7] She is a fellow of the American Association for the Advancement of Science and of SIAM.