The beginnings of this town can be traced back from the date it was made a visita of Milaor.

[5] It first started as a settlement in Western area of the Bicol River, then it grew to become a Sitio called Patong.

The name was changed to Pamplona by a retired Spanish military officer who resided in the place and named it after his native city in Spain - Pamplona, capital of Basque, Province of Navarro.

As part of the Bicol Region, the municipality has a tropical climate favorable to agriculture.

The rehabilitation of farm-to-market roads was started to link the barangays to the trade and commerce industry.

Pamplona is progressive due to its proximity to Pasacao port and the ever expanding Metro Naga.

Industrial plants, Resorts, Agriculture, being along the national road had create Pamplona to become the potential commercial center of Camarines Sur's second congressional district.

An ongoing project around Barangay Tambo is a 2-story mall with dining, parking, and hospital the end of the construction will be around the first and second quarter of 2025.

As of January 2023 the Business Park has a hotel, resort, gas station, Land Transportation Office, and several private running factories.