He briefly served as the caretaker Prime Minister of Greece from May 16, 2012 to June 20, 2012 after the legislative election in May 2012 resulted in an absence of majority.

He did postgraduate studies at Panthéon-Assas University,[3] and worked as a lawyer in Athens and London until becoming a rapporteur of the Council of State in 1976.

As well as his service in the judiciary, Pikrammenos has worked on a number of legislative committees for the Ministry of Justice and from 1991 to 1993 he was a special advisor on judicial affairs to Prime Minister Konstantinos Mitsotakis.

[4] Shortly after he was appointed as President of the Council of State in 2009, an explosive device was placed on Pikrammenos' car by what police believed to be an anarchist group.

[7] He was appointed caretaker prime minister by President Karolos Papoulias on 16 May 2012,[8] following the failure to form a government after the 6 May general elections.