The esports department of Panathinaikos was established on 29 December 2016.

[2][3][4][5] In order to launch the team, the club partnered with CowboyTV, a local game tournament organiser and owner of professional eSports team Void Gaming (established in late 2012).

The latter will remain active as the youth academy and official scrim partner of the club for League of Legends.

[6] The first teams that were announced will compete in the following titles: League of Legends,[7] Hearthstone,[8] and FIFA.

The establishment of an NBA 2K team was announced on 2 April 2020.