Panola is an unincorporated community and census-designated place (CDP) in Sumter County, Alabama, United States.

[3] The community's name comes from the Choctaw word ponola, which means "cotton".

[4] As of the 2020 United States Census, there were 71 people living in the CDP.

North Sumter Junior High School was previously in operation near, but not in, the Panola CDP.

This Sumter County, Alabama state location article is a stub.