Pantego is a town in Beaufort County, North Carolina, United States.

According to the United States Census Bureau, the town has a total area of 0.8 square miles (2.1 km2), all land.

About 4.9% of families and 7.9% of the population were below the poverty line, including 5.0% of those under the age of eighteen and 35.7% of those 65 or over.

It rolled along Pantego Creek, ran along one of its canals, Cuckold's Creek, and almost hit a railroad bridge and Highway 264, it took a turn, hit through a small marsh, split a house in half, and threw a truck over 40 feet high and threw it in a nearby field, the two occurred five feet from each other, the tornado then curved into a forest, destroying a Hardee's billboard, and rolled across the Cuckold's Creek again, and it slid along a field, until it curved into four houses on one side of the road, turned, hit another house across the street, hit another field.

Marc Van Essendelf, his seven children, and his wife, who was eight months pregnant, hid in a ditch; the house was splintered and obliterated.

The Pantego Academy was listed on the National Register of Historic Places in 1984.