Paolo Micallef (15 May 1818 - 8 March 1883) was a Maltese prelate who served as Archbishop of Pisa from 1871 until his death in 1883.

On 21 December 1863 Micallef was appointed as the Bishop of Città di Castello in Umbria.

He was consecrated bishop on 10 January 1864 in Rome by Cardinal Costantino Patrizi Naro.

In 1866, he was appointed as the Apostolic Administrator of the Diocese of Gozo in Malta after the death of its bishop, Michael Francis Buttigieg.

He held this post for two years until Antonio Grech Delicata was appointed as the new bishop of Gozo.