[4] Legend has it that the name Paombong was taken from the Tagalog word bumbong or tukil, the long bamboo tube used for collecting nipa sap.

Paombong was originally one of the visitas (barrio) of Malolos, mentioned in Capitulo XXXVI of Conquistas de Las Islas libro segundo by Fray Gaspar San Agustin.

In a meeting held in Tondo Convent, the Provincial Chapter created the Town of Malolos in June 1580 with Fray Matheo de Mendoza, OSA as its first minister, together with Barrios of Mambog under the patronage of San Roque, Matimbo with Santa Cruz and Paombong with Saint James Apostle.

Paombong is not wealthy as its neighbor towns of Malolos and Hagonoy at time and it did not sustain its township and it was degraded again as barrio and being a visita in 1638.

In the middle of the 1750s, Paombong grew into a modest community from what was once a cogon land inhabited by a handful of Tagalogs.

The seat of the local government was first established at the ground floor of the Paombong Church Convent then popularly called "zaguan".

Paombong is situated south-west of the province of Bulacan, with a total land area of 46.34 square kilometers (17.89 sq mi).

The municipality is approximately 47 kilometers (29 mi) from Metro Manila, it is a by-pass town and can be accessed via North Luzon Expressway and MacArthur Highway.

The San Pascual Baylon Maternity Hospital, situated at Barangay Santo Niño that offers secondary healthcare services.