A 12-episode anime television series adaptation, produced by Aniplex and studio Madhouse, aired on Fuji TV's Noitamina programming block from October to December 2005.

The students attempt to recruit Yukari as a model for their senior project at the school's upcoming fashion showcase, but she initially rejects them.

As Yukari spends more time at Paradise Kiss' studio, she begins skipping cram school to help with sewing beads onto their dress.

Despite their mutual attraction, Yukari finds herself frustrated at George's unpredictable and twisted behavior, as well as him prioritizing career and independence over love.

Inspired to be true to herself, Yukari tells her mother the truth but runs away from home and drops out of school after she opposes her decision.

Meanwhile, George is undecided about his career path, but his friend and senior, Kaori, visits him to convince him to continue studying design, which causes Yukari to become jealous.

[10] Tokyopop licensed Paradise Kiss for an English-language release in North America and serialized it in its manga magazine Smile.

[13] After Tokyopop's dissolving in 2011, New York based publishers Vertical acquired the rights to the property with plans on releasing the series in a three-volume A5 sized set with new covers, color plates and newly commissioned translation from September 2012 to March 2013.

While Geneon retained the license, Funimation Entertainment assumed exclusive rights to the manufacturing, marketing, sales and distribution of select titles.

In an interview in the January, 2007 issue of Newtype USA, director Kobayashi revealed many of the personal decisions which went into restructuring the manga into a television series.

[41] Wanting to avoid straying too far from the source material without approval, Kobayashi worked closely with Ai Yazawa on the new interpretations of the characters.

In many instances, Yazawa was concerned that taking the original material straight would distract casual viewers or worse drive them away.

In another instance of modification, this time brought by Kobayashi, the character design of Arashi was modified to suit a scruffier, less slick appearance.

So, Tayama mostly was involved in updating the clothes to suit the very latest hot trends, and touching up the designs to make them look and behave realistically when animated.

Carl Kimlinger of Anime News Network had a more positive view, saying that apart from the established characters, the show's true star is the "costume design" which is shown in much detail, with a "delicate balancing of realism with drama.