[1][2] Express train number RJ 1021 of the RegioJet company heading from Prague to Košice (3 cars should continue as RJ 1222 to Chop) collided with freight express train number Nex 41340 of the railway operator ČD Cargo.

[2] Pardubice is situated on one of the most important railway corridors in the Czech Republic, specifically on the Prague to Česká Třebová, and as such is used by trains heading towards Ostrava, Brno, Vienna, Budapest, Košice and Warsaw (eastbound) and towards Prague, Plzeň and Dresden (westbound), among many others.

Starting from 2021, the station underwent a major reconstruction program, the largest of its kind in over 60 years, which involved adding European Train Control System (ETCS), track remodelling works and the replacement of all adjacent infrastructure.

[5] The first train was RJ 1021 from Praha hlavní nádraží to Košice, with three through cars to Chop, Ukraine.

[7] Prime Minister Petr Fiala described the collision as a great tragedy and expressed his condolences to the families of the victims.