He continued to work for theatre and made his directorial debut for cinema with the 2009 Marathi feature film, Harishchandrachi Factory.

He currently lives in Mumbai and is married to theatre actor-writer Madhugandha Kulkarni, who had also done a minor role in Mokashi's debut film, Harishchandrachi Factory.

[2][3] Sangeet Debuchya Mulee made satirical comments on the current communal harmony in India, through the daughters of a saintly social reformer in Maharashtra, Debuji Zhingraji Janorkar, popularly known as Gadge Maharaj.

[2] His 2001 comedy play, Mukam Post Bombilwadi, showcased tumultuous events upon Adolf Hitler's accidental landing in a small village in coastal Maharashtra.

His other plays like Mangalawarache Mundake (2001) discussed environmental concerns and Samudra (2005), starring Atul Kulkarni, explored a mystery based upon ancient Vedic mythological history.

[12] Mokashi did a few small-time roles for Hindi TV serials and feature films, including Sanjay Leela Bhansali's Hum Dil De Chuke Sanam (1999) but soon he turned to writing and directing.

Ganesh Matkari of Pune Mirror was unimpressed with the film as "not Paresh Mokashi’s best work till date," but found it "reasonably amusing".

[25] Following a 5-year hiatus, Mokashi returned to film with the dark comedy Vaalvi, about a husband (Swapnil Joshi) planning to murder his mentally unstable wife (Anita Date-Kelkar).

Nandini Ramnath of Scroll.in was appreciative of Mokashi's direction and wrote, "The pitch-perfect cast has just the right attitude to a movie that invites us to consider the depth of human depravity and instead gives us an efficient and effective cruel comedy, as bloodless as it is ruthless".

[27] In January 2011, he inaugurated 5th National Book Exhibition at Nagpur and mentioned that if he hadn't read Dadasaheb Phalke's biography in 2005, he would not have made the film.

[29] In November 2011, Mokashi was made part of Disney and PVR Cinemas' joint initiative "My City My Parks", which focused on encouraging children about urban greenery.

The child participants of the event were asked to create a project on the topic of environmental conservation, in the form of a film, photo-journal, murals or a theatre performance.

[31] Mokashi was part of seminar session, "The Road Ahead: Globalism, the Digital Revolution and Other Attractions", with actor Kamal Haasan as its chairperson.

He was accompanied by another Marathi film director, Chandrakant Kulkarni, and was involved in two discussions, "Dadasaheb Phalke's cinematic journey" and "Hundred Years of Indian Cinema".