Previously the Paris-Sud Faculty of Sciences, the School assumed its current structure in 2019.

[1] Recent investments as part of the Paris-Saclay cluster have enlarged the School's faculty and upgraded its facilities.

[3] The Faculty has produced numerous research discoveries and many distinguished alumni and professors.

After World War II, the rapid growth of nuclear physics and chemistry meant that research needed more and more powerful accelerators, which required large areas.

The rapid increase of students led to the independence of the Orsay Center on March 1, 1965.