Players participate in a television quiz programme, answering questions in rounds of differing rules, earning or losing points along the way.

Up to five players are supported, and the game was released on the Nintendo Wii's Virtual Console in 2007.

The game plays like a real Japanese television quiz programme that airs on Channel 13 and is hosted by Tiger Yakuto: five contestants compete against each other in rounds of various quiz modes,[2] and up to five players can play simultaneously using the Mega Drive's Multiplayer Adaptor.

[4] Party Quiz Mega Q was released on the Virtual Console in Japan on 18 December 2007.

[7] It was included in the Japanese version of the Mega Drive Mini microconsole in September 2019, and two updated versions of the game with new questions, titled Party Quiz Mega Q 2022 and Party Quiz Sega Q (with Takenobu Mitsuyoshi replacing Tiger Yakuto as the host), were included in the Japanese edition of the follow-up system, the Mega Drive Mini 2, released on October 27, 2022.