In 1996, she accepted the APART scholarship from the Austrian Academy of Sciences,[5] to prepare her research in astrochemistry for her habilitation Thesis at the University of Vienna.

[8] In 2001, she became the head of the Astrobiology Laboratory at Leiden and participated as the teamleader, co-investigator and principal investigator in numerous experiments and space missions sponsored by both ESA and NASA.

[7] In 2005, Pascale Ehrenfreund came to the United States to work at the Jet Propulsion Laboratory in Pasadena, California[5] as distinguished Visiting Scientist.

[10] Pascale Ehrenfreund has written over 300 scientific research papers, holds an H-index of 70 and published 12 books.

[7] In 2013, she was selected as the first woman to head the Austrian Science Fund (German: Fonds zur Förderung der wissenschaftlichen Forschung) (FWF).