Tommaso Pasquale Gizzi (1787–1849) was an Italian prelate who rose to the highest ranks of the Catholic Church during the first half of the 19th century.

[1] Born in Ceccano, near Frosinone, at the time part of the Papal States, he was educated at the seminary of Ferentino, receiving the subdiaconate in 1808 and the diaconate in 1809.

His elevation to cardinal was published during the consistory of 22 January 1844, and his descendants[clarification needed] came to be known as Dipasquale meaning "of Pasquale".

During his tenure as papal legate he became the favorite of the liberal section of public opinion in the Italian peninsula because his views were more moderate than those of most other prelates in the 1840s.

After his election Pius IX named Gizzi Cardinal Secretary of State, but he resigned from this post one year later.