Indian mounds can be found throughout the Gulf coast region of southern Mississippi, but many have been destroyed by artifact hunters, farmers, developers, and flooding.

The mounds and middens in the area containing arrowheads, pottery, and human skeletons were pilfered by amateur archaeologists over the years and many of the items recovered are in private collections.

In spite of the fact that the beachfront Scenic Drive follows the crest of a small bluff, affording it some elevation, most of the historic mansions along the road were severely damaged, and many were completely destroyed, including the superbly restored Greek Revival mansion "Union Quarters" described in the National Register of Historic Places as having been built in 1855.

One car struck the south side doors, causing them to implode, and the Gulf of Mexico driven by Katrina's powerful winds rushed into the building.

Police Chief John Dubbisson swam to the rear doors that had to be opened where he successfully touched the push bar.

[12][13] The storm surge from Hurricane Katrina that hit Pass Christian was estimated at 8.5 m (27.8 ft),[14] which is the US record high,[15] leveling Pass Christian up to half a mile inland from the shore; estimation of highest storm surges was complicated because high-water markers were also destroyed.

Sewage contamination rendered the local water supply unusable, as some samples tested positive for more than 250 bacteria and parasites.

By late September 2005, access was restricted south of the railroad tracks (about four blocks inland) without proper credentials, as crews continued to search for victims and clear debris.

By early 2007, although rebuilding was underway in much of the city, a large portion of empty, deserted homes and other structures remain.

Geographically, the town of Pass Christian located on the Mississippi Sound, and is situated on a peninsula, with water on three sides: the Gulf of Mexico to the south, the Bay of St. Louis to the west and a long stretch of bayou to the north.

The unincorporated area north of the bayou, known as DeLisle, shares a zip code with Pass Christian, but is not within the city limits.

[18] DuPont DeLisle's titanium dioxide plant reported the third highest amount of dioxin-like compounds in EPA's Toxic Release Inventory (TRI).

Unlike other aquatic organisms, blue crabs do not have the ability to metabolize quickly certain dioxin-like compounds Polychlorinated dibenzofurans that predominate in the coke and ore solids waste stream of the plant.

The Deepwater Horizon oil spill, which occurred in the spring and summer of 2010—along with the presence of toxic sediments stirred up by Hurricane Katrina and record amounts of fresh water diverted into the Bonnet Carre Spillway in Louisiana—have brought seafood production to a standstill.

According to research from The Nature Conservancy, "roughly 13 years ago, Mississippi was harvesting nearly 500,000 sacks of oysters annually ....".

[22] Woodrow Wilson stayed a winter at Beaulieu when it was owned by John M. Ayer of New Jersey and leased by Herndons family.

[24] Board of Aldermen (2023) Naval Construction Battalion Center Gulfport, Mississippi, launched Seabees on Sept. 9 to neighboring communities throughout Harrison and Stone counties, including Pass Christian, to assist its citizens with disaster recovery in the wake of Hurricane Katrina.

250 Seabees from detachments across the United States gathered behind the city's War Memorial Park, where they constructed a temporary police department headquarters and other municipal offices.

The naval construction teams performed a similar feat after Hurricane Camille struck the town hard in 1969.