The San Marco Pass (Italian: Passo San Marco) is a mountain pass that links Val Brembana with Valtellina in the Bergamo Alps.

In the late years of the century the Republic of Venice decided to build a new road, that without crossing the Duchy of Milan, can create a new road ties between the Grisons and the Republic.

So the paved road of San Marco Pass was built.

Close to the pass at 1830 m above the sea level there is Ca San Marco a house also built in the late 16th century to provide care to the travelers during winter time.

The Giro d'Italia climbs San Marco Pass during the 2007 edition.