He notably won the mixed doubles championships at Wimbledon in 1928 with Elizabeth Ryan and at the French Open in 1931 with Betty Nuthall.

Patrick Spence began his tennis prominence in Great Britain in 1922 when he became Scottish champion after winning the local tournament.

[7] A week later, at the Surrey Hard Court Championships, he defeated Randolph Lycett of Australia in straight sets.

[9] In September he won the North London Hard Courts Championships on clay at the Gipsy Lawn Tennis Club, Stamford Hill against Harry Lewis-Barclay.

[13] In 1927 Spence reached the semi-finals of the French championships, beating Frank Hunter before losing to René Lacoste.

[17] However, he was more successful in his mixed doubles matches, including the final of the Nottingham Championships, which he won with Betty Nuthall.

[19] Also in 1930 he lost the London Covered Courts Championships to Yoshiro Ohta, but as many times before he was triumphant in the mixed contest with his recurring partner Nuthall.

[20] In 1931, he was a runner-up for the doubles tournament of the West-England Championships with Edward Avory, losing to the Japanese pair of Jiro Satoh and Ryuki Miki.

[3] A couple of years later, in 1935, he reached the final of the Surrey Grass Court Championships, where he was stopped by New Zealand's Eskell D.

[3] He married Joy Robson, a ballerina with Sadler Wells Ballet, and had four children: Mikael, Stephen, Mandy and Charles British Davis Cup team member Nigel Sharpe described him as an attacking type of player.