[1] As Metropolitan of Caesarea, his more important act was restoring in 1728 the monastery of Saint John the Baptist at Zincidere in Cappadocia.

[1] Neophytus VI was appointed as Patriarch on 27 September 1734[2] supported by the Dragoman of the Porte, the Phanariot Alexander Gikas.

[3] His subjection to the Dragoman caused the Grand vizier to order his deposition six years later, in August 1740.

[4] His Patriarchal reign was not marked by any particular event, and Neophytus VI mainly dealt with monastic issues.

He had letters with Nicolaus Zinzendorf, the reformer of the Moravian Church, but without any result.