[2]: 198 His first reign lasted only about one year because in early 1504 Joachim I returned to the throne after a payment of 3500 gold pieces to the Sultan.
The main issue during Pachomius I's patriarchate was the case of the Cretan scholar Arsenius Apostolius.
In 1506[4] the Roman Curia appointed Arsenius as Byzantine Rite bishop of Monemvasia, at that time part of the Stato da Màr of the Republic of Venice.
[3] This position was untenable for the Church of Constantinople and Pachomius I invited Arsenius to abdicate.
The issue went on for more than two years until June 1509 when Pachomius I excommunicated Arsenius, who retired to Venice.