Prior to her service in the municipal government, Paputsakis served as a substitute member Chamber of Deputies from Tarija, representing circumscription 45 under Víctor Hugo Zamora from 2010 to 2014 on behalf of the National Convergence alliance.

[3] Paputsakis studied law and political science at Juan Misael Saracho University, graduating with a diploma in pedagogical theory and practice and another in gender violence and women's human rights.

[1][4] As with many former student unionists, upon leaving university, Paputsakis sought to enter the political field, joining United to Renew (UNIR), the party of Tarija Mayor Oscar Montes.

In 2009, as part of UNIR's alliance with National Convergence (CN), she was elected to represent Tarija's circumscription 45 in the Chamber of Deputies, serving as a substitute under Víctor Hugo Zamora.

[11] The TSE's determination was opposed by ruling party and opposition parliamentarians alike, including Paputsakis, who stood to be disqualified despite only having spent a week a month in La Paz during her tenure.

Finally, on 19 March, just ten days before the election, the Departmental Electoral Tribunal of Tarija disqualified Paputsakis, stating that since she became a titular deputy following Zamora's resignation, she was subject to the TSE's ruling.

The electoral authority's decision came in response to a "semi-anonymous suit" filed by Daniela Aspiazu, which El País interpreted as a "maneuver" born from UNIR's leader, Montes, who quickly moved to replace Paputsakis's name on the ballot with that of Ruth Ponce, his own wife.

Ponce's sudden designation was understood to be a sign of simmering mistrust between Montes and his elected mayoral successor, Rodrigo Paz, with Paputsakis's deposition being the "first hostile act" in their eventual schism.

In prevention, the Secretariat collaborated with educational institutions and school psychologists to improve public understanding of subjects related to domestic violence, child sexual abuse, teenage pregnancy, and human trafficking, with the aim of reducing such problems.

As part of this, the Secretariat deployed Municipal Prevention Brigades in over seventy educational institutions, offering workshops to primary and secondary students to train them in recognizing signs of sexual abuse and violence by or between parents.

[38] Her candidacy was facilitated by Nationalist Democratic Action (ADN) and Solidarity Civic Unity (UCS), forming the electoral alliance Sustainable Base for Tarija (BASTA).