[6] In August 1948, the Brothers received a letter from Archbishop O'Brien on behalf of Norman Cardinal Gilroy, requesting staff for a new boys' school planned for Fairfield.

At this time, Fairfield was an outer and rapidly expanding suburb of Sydney with a large concentration of post war migrants from Europe.

[7] That pattern of building was retained and was repeated regularly to cope with the expanding enrolment which ten years later had reached almost one thousand.

The grounds in which the school was situated were a disused orchard and vineyard – uneven and ungrassed and abounding in powdery surface soil.

In the early sixties, the Brothers, supported by parents and students, embarked on a levelling, grass-planting and tree-planting campaign which was the foundation of the environment in which today's large complex is situated.

[8] On 25 June 2000, several years of construction on the campus came to an end with the official opening and blessing of the new College facilities and classrooms.

The old Year 8, 9, 10, and Primary blocks made way for an entirely new complex of buildings including a new library, Science wing, College hall and gymnasium, and Music and Creative Arts centre.

At the end of 2006, Patrician Brothers' College Primary School closed, and the grounds were returned to the Our Lady of the Rosary Parish to use.

The WYD cross and icon was hosted Patrician Brothers College, Fairfield for three hours that day for public veneration, which was attended by 5,000 people.

Bernard Bulfin, retired, and was replaced by the college's first lay principal, Michael Krawec, ending 48 years of leadership by the Brothers of St. Patrick.

During 2007, Michael Krawec, was appointed to the Catholic Education Office and the governors elected Wayne Marshall as the temporary Principal.

The College recently purchased and installed new computers in the Information and Technology Centre, new laptops and light probe projectors, 5 portable projection systems which are used for student presentations in the ITC, TAS and science blocks, a new computer lab in the science block, and several touch sensitive SmartBoards.

With the provision of the Rudd government's "Digital Education Revolution" Patrician Brothers College Fairfield will be one of the first schools to provide specially customised Apple MacBook's to over 400 Years 9 and 10 students in 2009.

Patrician Brothers' College, Fairfield, is recognised as a "famed renowned rugby league nursery, "[9] with many notable players going on to represent various NRL teams and achieving state and national honours.