Patrick Calhoun Caldwell (March 10, 1801 – November 22, 1855) was a U.S. Representative from South Carolina.
He was admitted to the bar in 1822 and commenced practice in South Carolina.
He served as member of the South Carolina State House of Representatives 1838–1839.
He was an unsuccessful candidate for reelection to the Twenty-eighth Congress.
He served in the South Carolina State Senate in 1848.