Patrick H. O'Farrell is a molecular biologist who made crucial contribution to the development of 2-dimensional protein electrophoresis[1] and Drosophila genetics.

He is now a professor of Biochemistry at the University of California, San Francisco (UCSF)[2] and has a h-index of 67.

[3] O'Farrell received his bachelor of science in 1969 from McGill University in Montreal, Quebec.

Two parameters were used: This permitted the simultaneous determination of molecular weight and isoelectric point for the proteins.

Because the two parameters are unrelated, it was possible to obtain an almost uniform distribution of protein spots across the two-dimensional gel.