[7] Newly elected President John Momis appointed Nisira as his vice-president on 10 June 2010—the same date as his presidential inauguration.
[8] Nisira resigned the Vice-Presidency in February 2017 in order to contest the 2017 Papua New Guinean national election.
In that role, he is working as part of the commission to ensure that the referendum on Bougainville's long term political future is conducted freely and fairly.
He is one of five Commissioners, that includes former Irish Prime Minister Bertie Ahern as chair.
On 2 October 2020 Nisira was appointed Minister of Economic Development in the cabinet of Ishmael Toroama.