He followed James VI of Scotland to England on his accession in 1603.
In June 1618 he was engaged in the work of raising voluntary gifts for the supply of the king's exchequer by threatening persons with prosecutions for usury.
Six years later (August 1624) King James I wrote a letter of recommendation on his behalf.
Scot apparently acted as occasional tutor to Prince Charles.
Scot's position resembled those of Joseph Hall and Thomas Tymme, with emphasis on unity of doctrine.