In the beginning of the 2013 season, Twumasi scored six goals in the first nine matches and was named Latvian Higher League player of the month in May 2013.

[1] In July 2013, Twumasi joined the Kazakhstan Premier League club FC Astana on loan from Spartaks Jūrmala.

Twumasi signed permanently for FC Astana prior to the 2015 season, despite attracting attention from other European clubs.

[7] On 16 August 2019, Twumasi signed a one-year loan deal with Turkish Süper Lig club Gaziantep.

[15] Twumasi was called up to the senior Ghana squad by Avram Grant for a 2017 Africa Cup of Nations qualifier against Mauritius in June 2016.