Colombani earned his medical degree from the University of Kentucky College of Medicine and completed residencies specializing in general surgery and pediatric surgery at the George Washington University School of Medicine and Johns Hopkins University School of Medicine, respectively.
[1][2] He then joined the Johns Hopkins School of Medicine faculty, where he taught as Robert Garrett Professor of Pediatric Surgery.
Colombani later earned a master's in business administration from Johns Hopkins University.
[3] In 2018, Paul Colombani resigned as surgery department chair of Johns Hopkins, and his name was removed from the hospital's website.
[6] In 2008, Colombani was named in a lawsuit in which an esteemed female doctor alleged gender discrimination and bullying.