Previously played for the Blackwater Bossing of the Philippine Basketball Association (PBA), he was also a former collegiate star player for the UP Fighting Maroons.
[5] He became Juniors MVP and made it to the Finals in 2011 against the Sacred Heart School – Ateneo de Cebu Magis Eagles.
[8] He played in the 2013 SEAOIL NBTC Games, which showcases many players from various high schools around the country.
[16] In the preseason, Desiderio and the Maroons won the Filsports Basketball Association (FBA) championship.
[18] They captured their second straight win in a row against the DLSU Green Archers, 71–66, with Desiderio scoring 13 points.
Desiderio set the screen on Adamson import Papi Sarr which enabled Akhuetie to hit the game-winning shot.
But with six seconds remaining, Desiderio hit a mid-range jumper over Sean Manganti for UP to win 89–87.
[59] Days after the draft, he was then sent to the Blackwater Elite along with Michael Miranda and Abu Tratter for big man Poy Erram and a second round pick in a three team trade with the TNT Katropa.
[60] In his first game for the Elite, Desiderio debuted with just five points on 2-of-6 shooting in a 117–91 loss to the Northport Batang Pier.
[65] He missed most of the 2020 Philippine Cup due to a grave leg muscle sprain and left the PBA bubble.
[67] That conference, he had eight points in a win over the Magnolia Hotshots that ended Blackwater's 29–game losing streak.
[68] Before the start of the 2022–23 PBA season, Desiderio suffered an injury in a tuneup game against the TNT Tropang Giga.
On September 14, 2022, while on the unrestricted free agent with rights to salary (UFAWR2S) list of Blackwater, it was initially reported that Desiderio's rights will be traded to the NLEX Road Warriors in a three-team trade involving Blackwater, NLEX, and TNT Tropang Giga.
[70] However, the trade version that was approved on September 19 included two future draft picks, not Desiderio's rights.
[71] Shortly after the trade's approval, Desiderio announced his retirement from the PBA, citing that he is going back to his native Cebu to allow his ACL injury to heal and to start a new life.
[72] On November 13, 2022, it was announced that Desiderio would be joining Talisay EGS for the 2022 Chooks-to-Go Pilipinas 3×3 Quest 2.0.
[74] In 2023, during the Al Bidda Park Challenger, Desiderio led the Manila Chooks to an upset win over Antwerp, which ranked third in the Fiba World Tour standings.
[76] He averaged 11 points and nearly 7 rebounds a game as the team made it all the way to the Finals, qualifying them for next year's 2014 FIBA Under-17 World Championship.
[79] Desiderio was also named to the "23-for-2023" pool, which was composed of young players for the 2023 FIBA World Cup.
She stated that Desiderio strangled, punched, kicked and hit her during their relationship, even when she was pregnant with their son.
He has his own Chooks-to-Go branch and he and his former fiancée opened a franchise of Kurimi Milk Tea Bar.