Over a career spanning several decades he trained numerous individuals in clinical cardiology who went on to leadership positions in academia throughout this country.
[1] Yu performed pioneering research in cardiac physiology, making seminal observations about the pulmonary circulation in health and disease, and the relationship to ventricular function, and key observations about the care of patients with coronary artery disease.
He served in numerous leadership roles during his career, including a term as President of the American Heart Association (1972-3).
Yu served on the editorial boards of the American Heart Journal, Circulation and the Journal of Electrocardiology and was a senior editor of Modern Concepts of Cardiovascular Disease, co-editor of the 16-volume Progress in Cardiology and author of the textbook Pulmonary Blood Volume in Health and Disease.
The Paul N. Yu Heart Center contains clinical inpatient and outpatient facilities for the treatment of Cardiovascular disease at Strong Memorial Hospital, with Nuclear Cardiology, Echocardiography, Electrophysiology, Interventional Cardiology Laboratories as well as Cardiac Rehabilitation facilities.