[2] As a senior, he averaged 18.2 points and 11.4 rebounds and was named the Central Florida Player of the Year as he led the Mustangs to the state championship game.

[10][11] In the 2019 College Basketball Invitational Reed averaged 18.3 points, 10.3 rebounds, 2.7 blocks, and 2.2 steals as he helped lead the Blue Demons to the best-of-three final.

[13] Reed recorded ten double-doubles and was named to the Big East Weekly Honor Roll four times during DePaul's 13-game non-conference schedule at the start of the season.

[21][22] On December 3, he signed with the 76ers on a two-way contract, meaning he would split time between the 76ers and their G League affiliate, the Delaware Blue Coats.

[23][24] Reed made his NBA debut on January 4, 2021, playing the final 90 seconds of the game and scoring two points on his sole field goal attempt in a 118–101 win over the Charlotte Hornets.

[29] On May 2, 2023, Reed sank four clutch free throws, leading the Philadelphia 76ers to win Game 1 of the Eastern Conference Semi-finals against the Boston Celtics.

[43] 'Out the Mud' calls back to a tweet Paul posted when he didn't receive any playing time in a game.