Born in the United States, he helped lead the Spanish national team to a EuroBasket title in 2022.

Brown initially attended Centennial High School in his native Roswell, Georgia (United States).

He averaged 20.8 points as a senior and was named a fourth-team Parade All-American and the Georgia 5A player of the Year.

[20] On November 15, he made his debut for the Drive in a 112–103 loss to the Bakersfield Jam, recording 14 points, six rebounds and five assists in 33 minutes.

[23] Three days later, in just his third game for the Timberwolves, he was thrown into the starting line-up due to being the only healthy point guard on the team as Mo Williams and Zach LaVine were both out injured.

[24] He moved back to the bench the following game on February 2 with the return of Ricky Rubio from long-term injury.

His playing time drastically decreased as he managed just 1:29 minutes of action in the 94–100 loss to the Dallas Mavericks.

[29] Two days later, he made his season debut in a 113–101 win over the Delaware 87ers, recording 13 points, two rebounds, two assists and three steals in 23 minutes off the bench.

[31] He made his debut for the Suns four days later, recording 7 points, 5 assists, 2 rebounds and 1 steal in a 116–97 loss to the Indiana Pacers.

[42] On December 8, 2016, he signed a contract with the Zhejiang Golden Bulls of the Chinese Basketball Association to replace the injured Cady Lalanne.

[50] On February 10, 2019, Guangzhou Loong Lions of the Chinese Basketball Association was reported to have signed Brown.

[51][52] Brown made his debut for the Loong Lions two days later, scoring 17 points with 2 rebounds and a steal in a 97–93 victory over the Beijing Ducks.

[57] He left the team in early 2022 due to the 2022 Russian invasion of Ukraine, but returned later to finish the season.

[44] On June 29, 2022, Brown signed a two-year deal with Israeli club Maccabi Tel Aviv.

[61] On June 19, 2024, Brown agreed upon a three-year contract, worth 5.4 million euros (along with a €600.000 buy-out compensation for Maccabi), with the reigning EuroLeague champions Panathinaikos.

After being a naturalization target for Croatia,[62][63][64] Brown was granted Spanish citizenship in early July 2022 ahead of EuroBasket 2022.