In 1983, Volberding founded the first inpatient ward for persons with AIDS in the San Francisco General Hospital.
[1] He worked on early clinical trials to evaluate antiretroviral therapy in HIV infection, and has served on the two major guidelines panels for antiretroviral therapy, addressing issues such as the optimal timing of treatment in early HIV infection when no symptoms are evident.
[3] In 2001 Volberding left the SF General Hospital to become chief medical officer at the San Francisco VA Medical Center, at which time he also became vice chairman of the department of medicine at the University of California, San Francisco (UCSF).
[4] He went on to become the co-director of the Center for AIDS Research (CFAR) at UCSF and the Gladstone Institute of Virology and Immunology.
[2] Volberding is also the co-editor of the Journal of Acquired Immune Deficiency Syndromes[5] and the editor-in-chief of Current HIV/AIDS Reports.