She is more recently known for her role in the popular Netflix series, Narcos, as the devoted young wife of Colombian drug kingpin Pablo Escobar.

[3] She was the female lead in the Cary Joji Fukunaga film Sin Nombre, where she played the character of Sayra, who joins her father and uncle when they try to migrate from Honduras to the United States, and ends up travelling with El Casper, a gang member, played by actor Edgar Flores.

[4] Gaitán also played a girl kidnapped by sex traffickers in the 2007 movie Trade alongside Kevin Kline.

[5] In addition, she has played the role of Zuvely in the short film En Tus Manos, which was also released in 2010.

In 2018, she began starring as Violetta, the female lead in the Amazon Prime Original Series Diablo Guardián.