[4] Latham was a Conservative member of Derbyshire County Council from 1987 to 1993, and was a Derby City Councillor from 1992 to 1996 and from 1998 to 2010.
[8] At the 2001 general election, Latham stood as the Conservative candidate in Broxtowe, coming second with 36.7% of the vote behind the incumbent Labour MP Nick Palmer.
[16] In February 2017, Latham said that other governments across Europe should be looking after refugee children from Calais in their jurisdictions, not Britain.
[17] At the snap 2017 general election, Latham was again re-elected, with an increased vote share of 58.6% and a decreased majority of 11,616.
[18] Latham voted for then Prime Minister Theresa May's Brexit withdrawal agreement on 29 March 2019.
[22] Following an interim report on the connections between colonialism and properties now in the care of the National Trust, including links with historic slavery, Latham was among the signatories of a letter to The Telegraph in November 2020 from the "Common Sense Group" of Conservative Parliamentarians.