Pauline van den Driessche (born 1941)[1] is a British and Canadian applied mathematician who is a professor emerita in the department of mathematics and statistics at the University of Victoria,[2] where she has also held an affiliation in the department of computer science.

[3] Her research interests include mathematical biology, matrix analysis, and stability theory.

Van den Driessche earned bachelor's and master's degrees in 1961 and 1963 respectively from Imperial College London.

She completed her doctorate in 1964 from the University College of Wales; her dissertation concerned fluid mechanics.

[4] In mathematical biology, van den Driessche's contributions include important work on delay differential equations and on Hopf bifurcations,[1][4] and the effects of changing population size and immigration on epidemics.