Interstate 35 bypasses the city on the west side, with access from Exits 99, 101, and 104.

[7] The climate in this area is characterized by hot, humid summers and generally mild to cool winters.

[8] As of the 2020 United States census, there were 7,325 people, 2,599 households, and 1,845 families residing in the city.

About 20.8% of all households were made up of individuals, and 9.9% had someone living alone who was 65 years of age or older.

The United States Postal Service operates the Pearsall Post Office.

[13] The U.S. Immigration and Customs Enforcement operates the South Texas Detention Facility in an unincorporated area in Frio County near Pearsall.